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Chapter 5

Membrane Transport and Cell Signaling

Essential Knowledge:
1.B.1: Organisms share many conserved core processes and features that evolved and are widely distributed among organisms today.
2.B.1: Cell membranes are selectively permeable due to their structure.
2.B.2: Growth and dynamic homeostasis are maintained by the constant movement of molecules across membranes.
3.D.2: Cells communicate with each other through direct contact with each other cells or from a distance via chemical signaling.

Learning Objectives:

2.10 Use representations and models to pose scientific questions about the properties of cell membranes and selective permeability based on molecular structure.
2.11 Construct models that connect the movement of molecules across membranes with membrane structure and function.
2.12 Use representations and models to analyze situations or solve problems qualitatively and quantitatively to investigate whether dynamic homeostasis is maintained by the active meovement of molecules across membranes.
3.31 Describe basic chemical processes for cell communication shared across evolutionary lines of descent.
3.32 Generate scientific questions involving cell communication as it relates to the process of evolution.
3.33 Use represntations and appropriate models to describe features of a cell-signaling pathway.
3.34 Construct explanations of cell communication through cell-to-cell direct contact or through chemical signaling.
3.35 Create representations that dpict how cell-to-cell communication occurs by direct contact or from a distance through chemical signaling.
3.36 Describe a model that expresses the key elements of signal transduction pathways by which a signal is converted to a cellular response.
3.37 Justify claims based on scientific evidence that changes in signal transduction pathways can alter cellular response.

Big Ideas:

 

The plasma membrane is a structure conserved across domains, yet highly specialized to species and their internal and external environments. Greater than the sum of its parts, it possesses emergent properties that regulate the complex interactions of cells.

Cell Membrane Rap

Bozeman Science: Cell Membranes

Bozeman Science: Transport Across Cell Membranes

Bozeman Science: Cell Communication

Scientific Skills Exercise:

Interpreting a scatter plot with two sets of data

   Is glucose uptake into cells affected by age?

​

Textbook page 109

Test Your Understanding

Textbook page 121, #1-6. 

As you complete test, mark questions with:

      a star (I know this),

      a checkmark (I might know this),

      or a question mark (I don't know, I guessed).

Self-correct.

Write validations/corrections for checkmarks, question marks, and missed stars (oops).

Illustrative

x

a

m

p

l

e

s

G-protein linked receptors
Glucose transport ligand
Gated ion channels
Second messengers: cAMP,   
   cGMP, calcium ions (Ca2+),
   and inositol triphosphate

Bubble Membrane Model

Plasmolysis

Tonicity

Agar Diffusion:

Surface Area-to-Volume

Concept

A

R

D

S

selective permeability
amphipathic
glycoproteins/glycolipids
transport proteins
aquaporins
osmoregulation
turgid/flaccid
plasmolysis

membrane potential

cotransport

hormones

ligand

G-protein

phosphorylation cascade

cyclic cAMP

fluid mosaic model
diffusion/osmosis
Tonicity: isotonic/hypertonic/hypotonic
Passive Transport/Active Transport/Facilitated Diffusion
Gradient: Concentration vs. Electrochemical
Cell Signaling Steps: Reception, Transduction, Response

Critical Thinking

A: In what ways are membranes crucial to life?

B: How do aquaporins affect the permeability of a membrane?

C: What happens to a cell placed in a hypertonic solution?

D: What happens to a cell placed in a hypotonic solution?

E: Describe what happens if a cell is placed into an isotonic solution.

F: ATP is not directly involved in the functioning of a cotransporter. Why then, is cotransport considered as active transport?

G: What determines whether a cell responds to a hormone such as epinephrine? What determines how the cell responds?

I can't see the forest for the trees...

Basic Biology Text:

Chapter 7 (All sections)

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At a minimum, understand:

Cell membranes are the regulators of all traffic entering and exiting the cell. They receive and send messages as well. Complex interactions can be carried out through cell membrane information interchange. Concentrations of solutes determine natural movement of substances in the cell, from high to low gradients.

"All who wander are not lost..."

IlexCanis, 2017
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